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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6 STAT1
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6 p-STAT1
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6 p-STAT6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6 STAT6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6 p-STAT4
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6 STAT4
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens